| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYT6 |
| Gene ID: | 148281 |
| Uniprot ID: | SYT6_HUMAN |
| Immunogen Region: | 1-120 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SYT6 (NP_001257734.1). |
| Immunogen Sequence: | MPWRNKEASSPSSANPPLEA LQSPSFRGNMADKLKDPSTL GFLEAAVKISHTSPDIPAEV QMSVKEHIMRHTRLQRQTTE PASSTRHTSFKRHLPRQMHV SSVDYGNELPPAAEQPTSIG |
| Function | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm. |
| Protein Name | Synaptotagmin-6Synaptotagmin ViSytvi |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneSingle-Pass Membrane ProteinIsoform 1: MembraneLocalized Predominantly To Endoplasmic Reticulum (Er) And/Or Golgi-Like Perinuclear CompartmentIsoform 2: CytoplasmCytosolCell MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Synaptotagmin-6 antibodyAnti-Synaptotagmin Vi antibodyAnti-Sytvi antibodyAnti-SYT6 antibody |
Information sourced from Uniprot.org