• Western blot analysis of various lysates using SYT6 Rabbit polyclonal antibody (STJ118611) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.

Anti-SYT6 antibody (1-120) (STJ118611)

SKU:
STJ118611

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SYT6 (1-120) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SYT6
Gene ID: 148281
Uniprot ID: SYT6_HUMAN
Immunogen Region: 1-120
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SYT6 (NP_001257734.1).
Immunogen Sequence: MPWRNKEASSPSSANPPLEA LQSPSFRGNMADKLKDPSTL GFLEAAVKISHTSPDIPAEV QMSVKEHIMRHTRLQRQTTE PASSTRHTSFKRHLPRQMHV SSVDYGNELPPAAEQPTSIG
Function May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm.
Protein Name Synaptotagmin-6
Synaptotagmin Vi
Sytvi
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Single-Pass Membrane Protein
Isoform 1: Membrane
Localized Predominantly To Endoplasmic Reticulum (Er) And/Or Golgi-Like Perinuclear Compartment
Isoform 2: Cytoplasm
Cytosol
Cell Membrane
Peripheral Membrane Protein
Alternative Antibody Names Anti-Synaptotagmin-6 antibody
Anti-Synaptotagmin Vi antibody
Anti-Sytvi antibody
Anti-SYT6 antibody

Information sourced from Uniprot.org

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