| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Symplekin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SYMPK |
| Gene ID: |
8189 |
| Uniprot ID: |
SYMPK_HUMAN |
| Specificity: |
This antibody detects endogenous levels of Symplekin at Human |
| Immunogen: |
Synthesized peptide derived from human Symplekin |
| Function | Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component. May have a house-keeping rule. Is involved in pre-mRNA polyadenylation. Enhances SSU72 phosphatase activity. |
| Protein Name | Symplekin |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionTight JunctionCell MembranePeripheral Membrane ProteinCytoplasmic SideNucleusNucleoplasmCytoplasmic Face Of Adhesion Plaques (Major) And Nucleoplasm (Minor) (In Cells With Tj)Nucleoplasm (In Cells Without Tj)Nuclear Bodies Of Heat-Stressed CellsColocalizes With Hsf1 In Nuclear Stress Bodies Upon Heat Shock |
| Alternative Antibody Names | Anti-Symplekin antibodyAnti-SYMPK antibodyAnti-SPK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
