• Immunofluorescence analysis of C6 cells using SYCP2 Rabbit polyclonal antibody (STJ118538) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using SYCP2 Rabbit polyclonal antibody (STJ118538) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SYCP2 antibody (1231-1530) (STJ118538)

SKU:
STJ118538

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SYCP2
Gene ID: 10388
Uniprot ID: SYCP2_HUMAN
Immunogen Region: 1231-1530
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1231-1530 of human SYCP2 (NP_055073.2).
Immunogen Sequence: EIESPHINENYIQSKREESH LASSLSKSSEGREKTWFDMP CDATHVSGPTQHLSRKRIYI EDNLSNSNEVEMEEKGERRA NLLPKKLCKIEDADHHIHKM SESVSSLSTNDFSIPWETWQ NEFAGIEMTYETYERLNSEF KRRNNIRHKMLSYFTTQSWK TAQQHLRTMNHQSQDSRIKK LDKFQFIIIEELENFEKDSQ SLKDLEKEFVDFWEKIFQKF SAYQKSEQQRLHLLKTSLA
Post Translational Modifications Phosphorylated.
Function Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.
Protein Name Synaptonemal Complex Protein 2
Scp-2
Synaptonemal Complex Lateral Element Protein
Hsscp2
Database Links Reactome: R-HSA-1221632
Cellular Localisation Nucleus
Chromosome
In Axial/Lateral Elements Of The Tripartite Segments Of Synaptonemal Complexes
Alternative Antibody Names Anti-Synaptonemal Complex Protein 2 antibody
Anti-Scp-2 antibody
Anti-Synaptonemal Complex Lateral Element Protein antibody
Anti-Hsscp2 antibody
Anti-SYCP2 antibody
Anti-SCP2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance