| Short Description : | Rabbit polyclonal SYCE1 (132-351) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYCE1 |
| Gene ID: | 93426 |
| Uniprot ID: | SYCE1_HUMAN |
| Immunogen Region: | 132-351 |
| Immunogen Sequence: | ECKERISALNLQIEEEKNKQ RQLRLAFEEQLEDLMGQHKD LWDFHMPERLAKEICALDSS KEQLLKEEKLVKATLEDVKH QLCSLCGAEGPSTLDEGLFL RSQEAAATVQLFQEEHRKAE ELLAAAAQRHQQLQQKCQQQ QQKRQRLKEELEKHGMQVPA QAQSTQEEEAGPGDVASPKP LKGERPGAAHQAGPDVLIGQ EDTLHPDLSPRGFQEIKELF |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1). |
| Function | Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination. |
| Protein Name | Synaptonemal Complex Central Element Protein 1Cancer/Testis Antigen 76Ct76 |
| Database Links | Reactome: R-HSA-1221632 |
| Cellular Localisation | NucleusChromosomeAssociates With ChromatinIn Prophase I Stage Of MeiosisLocalizes In The Transverse Central Elements Of The Central Region Between Lateral Elements Of The Synaptonemal ComplexesFound Only Where The Chromosome Cores Are SynapsedColocalizes With Syce2 In The Central Elements |
| Alternative Antibody Names | Anti-Synaptonemal Complex Central Element Protein 1 antibodyAnti-Cancer/Testis Antigen 76 antibodyAnti-Ct76 antibodyAnti-SYCE1 antibodyAnti-C10orf94 antibody |
Information sourced from Uniprot.org
