| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Sulfotransferase 2A1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SULT2A1 |
| Gene ID: | 6822 |
| Uniprot ID: | ST2A1_HUMAN |
| Specificity: | This antibody detects endogenous levels of human ST2A1 |
| Immunogen: | Synthesized peptide derived from the human ST2A1 |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism. In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols. |
| Protein Name | Sulfotransferase 2a1 St2a1 Bile Salt Sulfotransferase Dehydroepiandrosterone Sulfotransferase Dhea-St Dhea-St8 Hydroxysteroid Sulfotransferase Hst St2 Sult2a3 |
| Database Links | Reactome: R-HSA-156584 Reactome: R-HSA-1989781 Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sulfotransferase 2a1 antibody Anti-St2a1 antibody Anti-Bile Salt Sulfotransferase antibody Anti-Dehydroepiandrosterone Sulfotransferase antibody Anti-Dhea-St antibody Anti-Dhea-St8 antibody Anti-Hydroxysteroid Sulfotransferase antibody Anti-Hst antibody Anti-St2 antibody Anti-Sult2a3 antibody Anti-SULT2A1 antibody Anti-HST antibody Anti-STD antibody |
Information sourced from Uniprot.org