| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SULT1C4 |
| Gene ID: | 27233 |
| Uniprot ID: | ST1C4_HUMAN |
| Immunogen Region: | 1-95 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human SULT1C4 (NP_006579.2). |
| Immunogen Sequence: | MALHDMEDFTFDGTKRLSVN YVKGILQPTDTCDIWDKIWN FQAKPDDLLISTYPKAGTTW TQEIVELIQNEGDVEKSKRA PTHQRFPFLEMKIPS |
| Tissue Specificity | Expressed at high levels in fetal lung and kidney and at low levels in fetal heart, adult kidney, ovary and spinal chord. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic compounds. Can also sulfonate estrogenic compounds, however, the dietary flavonoids (phytoestrogen) and environmental estrogens, like bisphenol A are better substrates than 17beta-estradiol (E2). Mediates the sulfation of doxorubicin and its analog epirubicin, two antitumor anthracyclines. |
| Protein Name | Sulfotransferase 1c4St1c4Sulfotransferase 1c2Sult1c#2 |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-9753281 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Sulfotransferase 1c4 antibodyAnti-St1c4 antibodyAnti-Sulfotransferase 1c2 antibodyAnti-Sult1c#2 antibodyAnti-SULT1C4 antibodyAnti-SULT1C2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and BRD7 knockout (KO) 293T cells, using [KO Validated] BRD7 Rabbit polyclonal antibody (STJ22836) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99228/383979/STJ22836_1__90057.1713152605.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and BRD7 knockout (KO) 293T cells, using [KO Validated] BRD7 Rabbit polyclonal antibody (STJ22836) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.")
