| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:200-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SUCLG1 |
| Gene ID: | 8802 |
| Uniprot ID: | SUCA_HUMAN |
| Immunogen Region: | 41-346 |
| Immunogen Sequence: | CSYTASRQHLYVDKNTKIIC QGFTGKQGTFHSQQALEYGT KLVGGTTPGKGGQTHLGLPV FNTVKEAKEQTGATASVIYV PPPFAAAAINEAIEAEIPLV VCITEGIPQQDMVRVKHKLL RQEKTRLIGPNCPGVINPGE CKIGIMPGHIHKKGRIGIVS RSGTLTYEAVHQTTQVGLGQ SLCVGIGGDPFNGTDFIDCL EIFLNDSATEGIILIGEIGG NAEENAAEFLKQHNSGPNS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 41-346 of human SUCLG1 (NP_003840.2). |
| Function | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. |
| Protein Name | Succinate--Coa Ligase Adp/Gdp-Forming Subunit Alpha - MitochondrialSuccinyl-Coa Synthetase Subunit AlphaScs-Alpha |
| Database Links | Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Succinate--Coa Ligase Adp/Gdp-Forming Subunit Alpha - Mitochondrial antibodyAnti-Succinyl-Coa Synthetase Subunit Alpha antibodyAnti-Scs-Alpha antibodyAnti-SUCLG1 antibody |
Information sourced from Uniprot.org
