Anti-STX3 antibody (100-200) [S7MR] (STJ11101937)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Syntaxin 3 (100-200) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STX3 |
| Gene ID | 6809 |
| Uniprot ID | STX3_HUMAN |
| Immunogen Region | 100-200 |
| Immunogen Sequence | KHIEEDEVRSSADLRIRKSQ HSVLSRKFVEVMTKYNEAQV DFRERSKGRIQRQLEITGKK TTDEELEEMLESGNPAIFTS GIIDSQISKQALSEIEGRHK D |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Syntaxin 3 (Q13277). |
Additional Info
| Tissue Specificity | Isoform A: Expressed in small intestine, kidney, pancreas, placenta as well as in retina. Weaker expression in lung, liver and heart. Not expressed in brain and skeletal muscle. Isoform B: Expressed only in the retina. Isoform 3: Ubiquitously expressed. |
| Function | Potentially involved in docking of synaptic vesicles at presynaptic active zones. Apical receptor involved in membrane fusion of apical vesicles. Isoform B: Essential for survival of retinal photoreceetors. Isoform 3: Functions as a regulator of gene expression. |
| Protein Name | Syntaxin-3 |
| Database Links | Reactome: R-HSA-449836 |
| Cellular Localisation | Isoform A: Apical Cell MembraneSingle-Pass Type Iv Membrane ProteinLocalized To The Inner And Outer Plexiform LayersThe Cell Body And The Inner Segments Of PhotoreceptorsIsoform 3: Nucleus |
| Alternative Antibody Names | Anti-Syntaxin-3 antibodyAnti-STX3 antibodyAnti-STX3A antibody |
Information sourced from Uniprot.org