• Immunofluorescence analysis of HeLa cells, using STEA3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from COLO205 cells, using STEA3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using pHyde Polyclonal Antibody

Anti-STEAP3 antibody (421-470 aa) (STJ95072)

SKU:
STJ95072

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Metalloreductase STEAP3 (421-470 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STEAP3
Gene ID: 55240
Uniprot ID: STEA3_HUMAN
Immunogen Region: 421-470 aa
Specificity: pHyde Polyclonal Antibody detects endogenous levels of pHyde protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human STEA3 at the amino acid range 421-470
Post Translational Modifications Proteolytically cleaved by RHBDL4/RHBDD1. RHBDL4/RHBDD1-induced cleavage occurs at multiple sites in a glycosylation-independent manner. Glycosylated.
Function Integral membrane protein that functions as NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Mediates efficient transferrin-dependent iron uptake in erythroid cells. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Protein Name Metalloreductase Steap3
Dudulin-2
Six-Transmembrane Epithelial Antigen Of Prostate 3
Tumor Suppressor-Activated Pathway Protein 6
Htsap6
Phyde
Hphyde
Database Links Reactome: R-HSA-6803204
Reactome: R-HSA-9013148
Reactome: R-HSA-9013405
Reactome: R-HSA-9013406
Reactome: R-HSA-9013409
Reactome: R-HSA-9035034
Reactome: R-HSA-917977
Cellular Localisation Endosome Membrane
Multi-Pass Membrane Protein
Localizes To Vesicular-Like Structures At The Plasma Membrane And Around The Nucleus
Alternative Antibody Names Anti-Metalloreductase Steap3 antibody
Anti-Dudulin-2 antibody
Anti-Six-Transmembrane Epithelial Antigen Of Prostate 3 antibody
Anti-Tumor Suppressor-Activated Pathway Protein 6 antibody
Anti-Htsap6 antibody
Anti-Phyde antibody
Anti-Hphyde antibody
Anti-STEAP3 antibody
Anti-TSAP6 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance