Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-Staufen (478-577) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S8MR |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
STAU1 |
Gene ID: |
6780 |
Uniprot ID: |
STAU1_HUMAN |
Immunogen Region: |
478-577 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 478-577 of human Staufen (O95793). |
Immunogen Sequence: |
SGHVPHGPLTRPSEQLDYLS RVQGFQVEYKDFPKNNKNEF VSLINCSSQPPLISHGIGKD VESCHDMAALNILKLLSELD QQSTEMPRTGNGPMSVCGRC |
Tissue Specificity | Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta. |
Function | Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site. (Microbial infection) Plays a role in virus particles production of many viruses including of HIV-1, HERV-K, ebola virus and influenza virus. Acts by interacting with various viral proteins involved in particle budding process. |
Protein Name | Double-Stranded Rna-Binding Protein Staufen Homolog 1 |
Cellular Localisation | CytoplasmRough Endoplasmic ReticulumLocalizes Exclusively With The Rough Reticulum Endoplasmic (Rer) |
Alternative Antibody Names | Anti-Double-Stranded Rna-Binding Protein Staufen Homolog 1 antibodyAnti-STAU1 antibodyAnti-STAU antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance