• Western blot analysis of various lysates using STAT6 Rabbit polyclonal antibody (STJ11105475) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/ proteins: 25 Mu g per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-STAT6 antibody (748-847) (STJ11105475)

SKU:
STJ11105475

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Signal Transducer And Activator Of Transcription 6 (748-847) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STAT6
Gene ID: 6778
Uniprot ID: STAT6_HUMAN
Immunogen Region: 748-847
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 748-847 of human STAT6 (NP_003144.3).
Immunogen Sequence: QPQEHAVSSPDPLLCSDVTM VEDSCLSQPVTAFPQGTWIG EDIFPPLLPPTEQDLTKLLL EGQGESGGGSLGAQPLLQPS HYGQSGISMSHMDLRANPSW
Post Translational Modifications Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4. Tyrosine phosphorylated following stimulation by IL3/interleukin-3. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. Mono-ADP-ribosylated by PARP14.
Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.
Protein Name Signal Transducer And Activator Of Transcription 6
Il-4 Stat
Database Links Reactome: R-HSA-186763
Reactome: R-HSA-3249367
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Nucleus
Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names Anti-Signal Transducer And Activator Of Transcription 6 antibody
Anti-Il-4 Stat antibody
Anti-STAT6 antibody

Information sourced from Uniprot.org

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