Host: | Goat |
Applications: | Pep-ELISA/WB/IHC/FC |
Reactivity: | Human/Mouse/Rat/Dog/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-STAT5A (681-692) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-0.1-0.3µg/ml IHC-5µg/ml ELISA-antibody detection limit dilution 1:8000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | STAT5A |
Gene ID: | 6776 |
Uniprot ID: | STA5A_HUMAN |
Immunogen Region: | 681-692 |
Accession Number: | NP_003143.2 |
Specificity: | This antibody is not expected to cross-react with STAT5B. |
Immunogen Sequence: | KYYTPVLAKAVD |
Function | Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. |
Protein Name | Signal Transducer And Activator Of Transcription 5a |
Database Links | Reactome: R-HSA-1170546 Reactome: R-HSA-1251985 Reactome: R-HSA-1266695 Reactome: R-HSA-1433557 Reactome: R-HSA-1839117 Reactome: R-HSA-186763 Reactome: R-HSA-2586552 Reactome: R-HSA-512988 Reactome: R-HSA-8854691 Reactome: R-HSA-8983432 Reactome: R-HSA-8985947 Reactome: R-HSA-9020558 Reactome: R-HSA-9020958 Reactome: R-HSA-9027283 Reactome: R-HSA-9645135 Reactome: R-HSA-9670439 Reactome: R-HSA-9674555 Reactome: R-HSA-9702518 Reactome: R-HSA-9703465 Reactome: R-HSA-9705462 Reactome: R-HSA-9725371 Reactome: R-HSA-982772 |
Cellular Localisation | Cytoplasm Nucleus Translocated Into The Nucleus In Response To Phosphorylation |
Alternative Antibody Names | Anti-Signal Transducer And Activator Of Transcription 5a antibody Anti-STAT5A antibody Anti-STAT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance