| Short Description : | Rabbit polyclonal ST14 (566-855) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ST14 |
| Gene ID: | 6768 |
| Uniprot ID: | ST14_HUMAN |
| Immunogen Region: | 566-855 |
| Immunogen Sequence: | TCTKHTYRCLNGLCLSKGNP ECDGKEDCSDGSDEKDCDCG LRSFTRQARVVGGTDADEGE WPWQVSLHALGQGHICGASL ISPNWLVSAAHCYIDDRGFR YSDPTQWTAFLGLHDQSQRS APGVQERRLKRIISHPFFND FTFDYDIALLELEKPAEYSS MVRPICLPDASHVFPAGKAI WVTGWGHTQYGGTGALILQK GEIRVINQTTCENLLPQQIT PRMMCVGFLSGGVDSCQGD |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 566-855 of human ST14 (NP_068813.1). |
| Function | Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing. Proteolytically cleaves and therefore activates TMPRSS13. |
| Protein Name | Suppressor Of Tumorigenicity 14 ProteinMatriptaseMembrane-Type Serine Protease 1Mt-Sp1ProstaminSerine Protease 14Serine Protease Tadg-15Tumor-Associated Differentially-Expressed Gene 15 Protein |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Suppressor Of Tumorigenicity 14 Protein antibodyAnti-Matriptase antibodyAnti-Membrane-Type Serine Protease 1 antibodyAnti-Mt-Sp1 antibodyAnti-Prostamin antibodyAnti-Serine Protease 14 antibodyAnti-Serine Protease Tadg-15 antibodyAnti-Tumor-Associated Differentially-Expressed Gene 15 Protein antibodyAnti-ST14 antibodyAnti-PRSS14 antibodyAnti-SNC19 antibodyAnti-TADG15 antibody |
Information sourced from Uniprot.org
