| Short Description : | Rabbit polyclonal Serine/Arginine-Rich Splicing Factor 4 (1-180) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SRSF4 |
| Gene ID: | 6429 |
| Uniprot ID: | SRSF4_HUMAN |
| Immunogen Region: | 1-180 |
| Immunogen Sequence: | MPRVYIGRLSYQARERDVER FFKGYGKILEVDLKNGYGFV EFDDLRDADDAVYELNGKDL CGERVIVEHARGPRRDGSYG SGRSGYGYRRSGRDKYGPPT RTEYRLIVENLSSRCSWQDL KDYMRQAGEVTYADAHKGRK NEGVIEFVSYSDMKRALEKL DGTEVNGRKIRLVEDKPGSR |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SRSF4 (NP_005617.2). |
| Post Translational Modifications | Extensively phosphorylated on serine residues in the RS domain. |
| Function | Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. |
| Protein Name | Serine/Arginine-Rich Splicing Factor 4Pre-Mrna-Splicing Factor Srp75Srp001lbSplicing Factor - Arginine/Serine-Rich 4 |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856 |
| Cellular Localisation | Nucleus Speckle |
| Alternative Antibody Names | Anti-Serine/Arginine-Rich Splicing Factor 4 antibodyAnti-Pre-Mrna-Splicing Factor Srp75 antibodyAnti-Srp001lb antibodyAnti-Splicing Factor - Arginine/Serine-Rich 4 antibodyAnti-SRSF4 antibodyAnti-SFRS4 antibodyAnti-SRP75 antibody |
Information sourced from Uniprot.org
![Confocal immunofluorescence analysis of HeLa cells using [KO Validated] HNRNPA2B1 Rabbit polyclonal antibody (STJ24063) at dilution of 1:400. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99826/385443/STJ24063_1__97324.1713154337.jpg?c=1 "Confocal immunofluorescence analysis of HeLa cells using [KO Validated] HNRNPA2B1 Rabbit polyclonal antibody (STJ24063) at dilution of 1:400. Blue: DAPI for nuclear staining.")
