• Western blot analysis of various lysates using Serine racemase Rabbit monoclonal antibody (STJ11104208) at1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SRR antibody (1-100) [S4208RM] (STJ11104208)

SKU:
STJ11104208

£129.50 - £574.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Monoclonal
Clone ID: S4208RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SRR
Gene ID: 63826
Uniprot ID: SRR_HUMAN
Immunogen Region: 1-100
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Serine racemase (NP_068766.1).
Immunogen Sequence: MCAQYCISFADVEKAHINIR DSIHLTPVLTSSILNQLTGR NLFFKCELFQKTGSFKIRGA LNAVRSLVPDALERKPKAVV THSSGNHGQALTYAAKLEGI
Tissue Specificity Expressed in the cerebellum, hippocampus, dorsolateral prefrontal cortex, and in motor neurons and glial cells of the lumbar spinal cord (at protein level). Increased in the dorsolateral prefrontal cortex of schizophrenic patients (at protein level). Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney, and liver.
Post Translational Modifications S-nitrosylated, leading to decrease the enzyme activity.
Function Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Protein Name Serine Racemase
D-Serine Ammonia-Lyase
D-Serine Dehydratase
L-Serine Ammonia-Lyase
L-Serine Dehydratase
Database Links Reactome: R-HSA-977347
Alternative Antibody Names Anti-Serine Racemase antibody
Anti-D-Serine Ammonia-Lyase antibody
Anti-D-Serine Dehydratase antibody
Anti-L-Serine Ammonia-Lyase antibody
Anti-L-Serine Dehydratase antibody
Anti-SRR antibody

Information sourced from Uniprot.org

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