| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Serine Racemase (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4208RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SRR |
| Gene ID: |
63826 |
| Uniprot ID: |
SRR_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Serine racemase (NP_068766.1). |
| Immunogen Sequence: |
MCAQYCISFADVEKAHINIR DSIHLTPVLTSSILNQLTGR NLFFKCELFQKTGSFKIRGA LNAVRSLVPDALERKPKAVV THSSGNHGQALTYAAKLEGI |
| Tissue Specificity | Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver. |
| Post Translational Modifications | S-nitrosylated, leading to decrease the enzyme activity. |
| Function | Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. |
| Protein Name | Serine RacemaseD-Serine Ammonia-LyaseD-Serine DehydrataseL-Serine Ammonia-LyaseL-Serine Dehydratase |
| Database Links | Reactome: R-HSA-977347 |
| Alternative Antibody Names | Anti-Serine Racemase antibodyAnti-D-Serine Ammonia-Lyase antibodyAnti-D-Serine Dehydratase antibodyAnti-L-Serine Ammonia-Lyase antibodyAnti-L-Serine Dehydratase antibodyAnti-SRR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
