Host: |
Rabbit |
Applications: |
WB/IF/ICC/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SPINT2 |
Gene ID: |
10653 |
Uniprot ID: |
SPIT2_HUMAN |
Immunogen Region: |
28-197 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 28-197 of human SPINT2 (NP_066925.1). |
Immunogen Sequence: |
ADRERSIHDFCLVSKVVGRC RASMPRWWYNVTDGSCQLFV YGGCDGNSNNYLTKEECLKK CATVTENATGDLATSRNAAD SSVPSAPRRQDSEDHSSDMF NYEEYCTANAVTGPCRASFP RWYFDVERNSCNNFIYGGCR GNKNSYRSEEACMLRCFRQQ ENPPLPLGSK |
Tissue Specificity | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
Function | Inhibitor of HGFAC. Also inhibits plasmin, and plasma and tissue kallikrein. Inhibits serine protease activity of TMPRSS13. Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro. |
Protein Name | Kunitz-Type Protease Inhibitor 2Hepatocyte Growth Factor Activator Inhibitor Type 2Hai-2Placental Bikunin |
Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
Alternative Antibody Names | Anti-Kunitz-Type Protease Inhibitor 2 antibodyAnti-Hepatocyte Growth Factor Activator Inhibitor Type 2 antibodyAnti-Hai-2 antibodyAnti-Placental Bikunin antibodyAnti-SPINT2 antibodyAnti-HAI2 antibodyAnti-KOP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance