| Short Description : | Rabbit polyclonal SP110 (1-290) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SP110 |
| Gene ID: | 3431 |
| Uniprot ID: | SP110_HUMAN |
| Immunogen Region: | 1-290 |
| Immunogen Sequence: | MFTMTRAMEEALFQHFMHQK LGIAYAIHKPFPFFEGLLDN SIITKRMYMESLEACRNLIP VSRVVHNILTQLERTFNLSL LVTLFSQINLREYPNLVTIY RSFKRVGASYERQSRDTPIL LEAPTGLAEGSSLHTPLALP PPQPPQPSCSPCAPRVSEPG TSSQQSDEILSESPSPSDPV LPLPALIQEGRSTSVTNDKL TSKMNAEEDSEEMPSLLTST VQVASDNLIPQIRDKEDPQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human SP110 (NP_004501.3). |
| Tissue Specificity | Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Post Translational Modifications | Phosphorylated (isoform 2). |
| Function | Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE). |
| Protein Name | Sp110 Nuclear Body ProteinInterferon-Induced Protein 41/75Speckled 110 KdaTranscriptional Coactivator Sp110 |
| Database Links | |
| Cellular Localisation | NucleusFound In The Nuclear Body |
| Alternative Antibody Names | Anti-Sp110 Nuclear Body Protein antibodyAnti-Interferon-Induced Protein 41/75 antibodyAnti-Speckled 110 Kda antibodyAnti-Transcriptional Coactivator Sp110 antibodyAnti-SP110 antibody |
Information sourced from Uniprot.org
