| Host: |
Mouse |
| Applications: |
IHC-F/IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-SOX10 is suitable for use in Immunohistochemistry and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
SOX10/1074 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2bk |
| Formulation: |
Bioreactor Concentrate with 0.05% Azide |
| Purification: |
Concentrate |
| Dilution Range: |
IHC-FIHC-P 1:200-1:400 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Gene Symbol: |
SOX10 |
| Gene ID: |
6663 |
| Uniprot ID: |
SOX10_HUMAN |
| Immunogen: |
Recombinant fragment (155 Amino residues between aa 100-300) of human SOX10 protein |
| Tissue Specificity | Expressed in fetal brain and in adult brain, heart, small intestine and colon. |
| Function | Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter. |
| Protein Name | Transcription Factor Sox-10 |
| Database Links | Reactome: R-HSA-9619665Reactome: R-HSA-9764302 |
| Cellular Localisation | CytoplasmNucleusMitochondrion Outer MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Transcription Factor Sox-10 antibodyAnti-SOX10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
