Anti-SOX10 antibody [SOX10/1074] (STJ16101855)

SKU:
STJ16101855-1

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Host: Mouse
Applications: IHC-F/IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-SOX10 is suitable for use in Immunohistochemistry and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: SOX10/1074
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: Bioreactor Concentrate with 0.05% Azide
Purification: Concentrate
Dilution Range: IHC-F
IHC-P 1:200-1:400
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: SOX10
Gene ID: 6663
Uniprot ID: SOX10_HUMAN
Immunogen: Recombinant fragment (155 Amino residues between aa 100-300) of human SOX10 protein
Tissue Specificity Expressed in fetal brain and in adult brain, heart, small intestine and colon.
Function Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter.
Protein Name Transcription Factor Sox-10
Database Links Reactome: R-HSA-9619665
Reactome: R-HSA-9764302
Cellular Localisation Cytoplasm
Nucleus
Mitochondrion Outer Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Transcription Factor Sox-10 antibody
Anti-SOX10 antibody

Information sourced from Uniprot.org

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