| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SOSTDC1 |
| Gene ID: | 25928 |
| Uniprot ID: | SOSD1_HUMAN |
| Immunogen Region: | 115-206 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 115-206 of human SOSTDC1 (NP_056279.1). |
| Immunogen Sequence: | GGGYGTKYWSRRSSQEWRCV NDKTRTQRIQLQCQDGSTRT YKITVVTACKCKRYTRQHNE SSHNFESMSPAKPVQHHRER KRASKSSKHSMS |
| Tissue Specificity | Highly expressed in kidney and weakly in lung. |
| Function | May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. |
| Protein Name | Sclerostin Domain-Containing Protein 1Ectodermal Bmp InhibitorEctodinUterine Sensitization-Associated Gene 1 ProteinUsag-1 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Sclerostin Domain-Containing Protein 1 antibodyAnti-Ectodermal Bmp Inhibitor antibodyAnti-Ectodin antibodyAnti-Uterine Sensitization-Associated Gene 1 Protein antibodyAnti-Usag-1 antibodyAnti-SOSTDC1 antibodyAnti-USAG1 antibodyAnti-CDA019 antibody |
Information sourced from Uniprot.org