| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Sorbin and SH3 domain-containing protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SORBS1 |
| Gene ID: |
10580 |
| Uniprot ID: |
SRBS1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SORBS1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human SORBS1 |
| Post Translational Modifications | O-glycosylated. |
| Function | Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions. |
| Protein Name | Sorbin And Sh3 Domain-Containing Protein 1PonsinSh3 Domain Protein 5Sh3p12C-Cbl-Associated ProteinCap |
| Database Links | Reactome: R-HSA-445355 |
| Cellular Localisation | Cell JunctionAdherens JunctionCell MembraneCytoplasmCytoskeletonFocal AdhesionNucleusNucleus MatrixColocalizes With The Ten-1 Icd Form Of Tenm1 In The NucleusColocalizes With Actin Stress FibersAlso Detected At The Plasma Membrane And In Neuronal Intranuclear InclusionsColocalized With Pxn At Focal Adhesions During Myogenic Differentiation |
| Alternative Antibody Names | Anti-Sorbin And Sh3 Domain-Containing Protein 1 antibodyAnti-Ponsin antibodyAnti-Sh3 Domain Protein 5 antibodyAnti-Sh3p12 antibodyAnti-C-Cbl-Associated Protein antibodyAnti-Cap antibodyAnti-SORBS1 antibodyAnti-KIAA0894 antibodyAnti-KIAA1296 antibodyAnti-SH3D5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
