Anti-SORBS1 antibody (STJA0007466)

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STJA0007466
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Sorbin and SH3 domain-containing protein 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SORBS1
Gene ID:10580
Uniprot ID:SRBS1_HUMAN
Immunogen:Synthesized peptide derived from human SORBS1
Specificity:This antibody detects endogenous levels of SORBS1 at Human, Mouse, Rat
Post Translational Modifications O-glycosylated.
Function Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.
Protein Name Sorbin And Sh3 Domain-Containing Protein 1
Ponsin
Sh3 Domain Protein 5
Sh3p12
C-Cbl-Associated Protein
Cap
Database Links Reactome: R-HSA-445355
Cellular Localisation Cell Junction
Adherens Junction
Cell Membrane
Cytoplasm
Cytoskeleton
Focal Adhesion
Nucleus
Nucleus Matrix
Colocalizes With The Ten-1 Icd Form Of Tenm1 In The Nucleus
Colocalizes With Actin Stress Fibers
Also Detected At The Plasma Membrane And In Neuronal Intranuclear Inclusions
Colocalized With Pxn At Focal Adhesions During Myogenic Differentiation
Alternative Antibody Names Anti-Sorbin And Sh3 Domain-Containing Protein 1 antibody
Anti-Ponsin antibody
Anti-Sh3 Domain Protein 5 antibody
Anti-Sh3p12 antibody
Anti-C-Cbl-Associated Protein antibody
Anti-Cap antibody
Anti-SORBS1 antibody
Anti-KIAA0894 antibody
Anti-KIAA1296 antibody
Anti-SH3D5 antibody

Information sourced from Uniprot.org

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