| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SOCS4 (426-440) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SOCS4 |
| Gene ID: |
122809 |
| Uniprot ID: |
SOCS4_HUMAN |
| Immunogen Region: |
426-440 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 426-440 of human SOCS4 (NP_543143.1). |
| Immunogen Sequence: |
SKVRVLRIDAPEQQC |
| Function | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. |
| Protein Name | Suppressor Of Cytokine Signaling 4Socs-4Suppressor Of Cytokine Signaling 7Socs-7 |
| Database Links | Reactome: R-HSA-8939242 |
| Alternative Antibody Names | Anti-Suppressor Of Cytokine Signaling 4 antibodyAnti-Socs-4 antibodyAnti-Suppressor Of Cytokine Signaling 7 antibodyAnti-Socs-7 antibodyAnti-SOCS4 antibodyAnti-SOCS7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
