| Post Translational Modifications | Phosphorylated. |
| Function | Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP.this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes. |
| Protein Name | Sorting Nexin-33Sh3 And Px Domain-Containing Protein 3 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmic Vesicle MembranePrimarily CytosolicBut A Minor Proportion Is Membrane-BoundNot Associated With Membranes |
| Alternative Antibody Names | Anti-Sorting Nexin-33 antibodyAnti-Sh3 And Px Domain-Containing Protein 3 antibodyAnti-SNX33 antibodyAnti-SH3PX3 antibodyAnti-SH3PXD3C antibodyAnti-SNX30 antibody |
Information sourced from Uniprot.org
