| Host: |
Goat |
| Applications: |
Pep-ELISA/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-SNM1/DCLRE1A (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-5µg/mlELISA-antibody detection limit dilution 1:8000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
DCLRE1A |
| Gene ID: |
9937 |
| Uniprot ID: |
DCR1A_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_055696.3 |
| Immunogen Sequence: |
PSPNQKRSSQCKRK |
| Function | May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin. Exhibits no activity towards other beta-lactam antibiotic classes including cephalosporins (cefotaxime) and carbapenems (imipenem). |
| Protein Name | Dna Cross-Link Repair 1a ProteinBeta-Lactamase Dclre1aSnm1 Homolog AHsnm1Hsnm1a |
| Database Links | Reactome: R-HSA-6783310 |
| Cellular Localisation | NucleusIn Some Cells It May Be Found In Typically 1 Or 2 Discrete Nuclear Aggregates Of Unknown Function Which Also Contain Tp53bp1Also Found In Multiple Discrete Nuclear Foci Which Increase In Number Following Treatment With Ionizing Radiation Or Interstrand Cross-Linking AgentsThese Foci Overlap With Those Formed By The Mrn Complex (Composed Of Mre11Rad50 And Nbn) And Brca1 |
| Alternative Antibody Names | Anti-Dna Cross-Link Repair 1a Protein antibodyAnti-Beta-Lactamase Dclre1a antibodyAnti-Snm1 Homolog A antibodyAnti-Hsnm1 antibodyAnti-Hsnm1a antibodyAnti-DCLRE1A antibodyAnti-KIAA0086 antibodyAnti-SNM1 antibodyAnti-SNM1A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
