Host: |
Mouse |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Gamma-synuclein is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Monoclonal |
Clone ID: |
1H10D2 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1 |
Formulation: |
Liquid in PBS containing 0.03% Sodium Azide. |
Purification: |
Affinity purification |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:200-1:1000ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SNCG |
Gene ID: |
6623 |
Uniprot ID: |
SYUG_HUMAN |
Specificity: |
Synuclein-Gamma Monoclonal Antibody detects endogenous levels of Synuclein-Gamma protein. |
Immunogen: |
Purified recombinant fragment of Synuclein-Gamma expressed in E. Coli. |
Post Translational Modifications | Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases. |
Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. |
Protein Name | Gamma-SynucleinBreast Cancer-Specific Gene 1 ProteinPersynSynoretinSr |
Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleAssociated With Centrosomes In Several Interphase CellsIn Mitotic CellsLocalized To The Poles Of The Spindle |
Alternative Antibody Names | Anti-Gamma-Synuclein antibodyAnti-Breast Cancer-Specific Gene 1 Protein antibodyAnti-Persyn antibodyAnti-Synoretin antibodyAnti-Sr antibodyAnti-SNCG antibodyAnti-BCSG1 antibodyAnti-PERSYN antibodyAnti-PRSN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance