Immunohistochemistry analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right) , showing cytoplasmic (ovary carcinoma) localization, cytoplasmic and nuclear (breast carcinoma) localization with DAB staining using Synuclein-Gamma Mo

Anti-SNCG antibody [1H10D2] (STJ98409)

SKU:
STJ98409
£144.00 - £348.00
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Host: Mouse
Applications: WB/IHC/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Gamma-synuclein is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Monoclonal
Clone ID : 1H10D2
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide.
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SNCG
Gene ID: 6623
Uniprot ID: SYUG_HUMAN
Specificity: Synuclein-Gamma Monoclonal Antibody detects endogenous levels of Synuclein-Gamma protein.
Immunogen: Purified recombinant fragment of Synuclein-Gamma expressed in E. Coli.
Post Translational Modifications Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases.
Function Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
Protein Name Gamma-Synuclein
Breast Cancer-Specific Gene 1 Protein
Persyn
Synoretin
Sr
Cellular Localisation Cytoplasm
Perinuclear Region
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle
Associated With Centrosomes In Several Interphase Cells
In Mitotic Cells
Localized To The Poles Of The Spindle
Alternative Antibody Names Anti-Gamma-Synuclein antibody
Anti-Breast Cancer-Specific Gene 1 Protein antibody
Anti-Persyn antibody
Anti-Synoretin antibody
Anti-Sr antibody
Anti-SNCG antibody
Anti-BCSG1 antibody
Anti-PERSYN antibody
Anti-PRSN antibody

Information sourced from Uniprot.org

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