• Western blot analysis of lysates from HeLa cells, using Synuclein beta Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of A549 cells, using Synuclein beta Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Synuclein beta Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Synuclein-Beta Polyclonal Antibody

Anti-SNCB antibody (85-134 aa) (STJ95863)

SKU:
STJ95863

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Beta-synuclein (85-134 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SNCB
Gene ID: 6620
Uniprot ID: SYUB_HUMAN
Immunogen Region: 85-134 aa
Specificity: Synuclein-Beta Polyclonal Antibody detects endogenous levels of Synuclein-Beta protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Synuclein beta at the amino acid range 85-134
Post Translational Modifications Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.
Function Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Protein Name Beta-Synuclein
Database Links Reactome: R-HSA-5660489
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Beta-Synuclein antibody
Anti-SNCB antibody

Information sourced from Uniprot.org

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