• Western blot analysis of various lysates using SMPD2 Rabbit polyclonal antibody (STJ25629) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SMPD2 antibody (150-250) (STJ25629)

SKU:
STJ25629

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SMPD2 (150-250) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SMPD2
Gene ID: 6610
Uniprot ID: NSMA_HUMAN
Immunogen Region: 150-250
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMPD2 (NP_003071.2).
Immunogen Sequence: AHRVAQAWELAQFIHHTSKK ADVVLLCGDLNMHPEDLGCC LLKEWTGLHDAYLETRDFKG SEEGNTMVPKNCYVSQQELK PFPFGVRIDYVLYKAVSGFY I
Function Catalyzes, at least in vitro, the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Also hydrolyzes 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) in vivo. Also acts on 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and sphingosylphosphocholine.
Protein Name Sphingomyelin Phosphodiesterase 2
Lyso-Platelet-Activating Factor-Phospholipase C
Lyso-Paf-Plc
Neutral Sphingomyelinase
N-Smase
Nsmase
Nsmase1
Database Links Reactome: R-HSA-1660662
Reactome: R-HSA-193681
Reactome: R-HSA-5626978
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Sphingomyelin Phosphodiesterase 2 antibody
Anti-Lyso-Platelet-Activating Factor-Phospholipase C antibody
Anti-Lyso-Paf-Plc antibody
Anti-Neutral Sphingomyelinase antibody
Anti-N-Smase antibody
Anti-Nsmase antibody
Anti-Nsmase1 antibody
Anti-SMPD2 antibody

Information sourced from Uniprot.org

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