| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SMPD2 |
| Gene ID: | 6610 |
| Uniprot ID: | NSMA_HUMAN |
| Immunogen Region: | 150-250 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMPD2 (NP_003071.2). |
| Immunogen Sequence: | AHRVAQAWELAQFIHHTSKK ADVVLLCGDLNMHPEDLGCC LLKEWTGLHDAYLETRDFKG SEEGNTMVPKNCYVSQQELK PFPFGVRIDYVLYKAVSGFY I |
| Function | Catalyzes, at least in vitro, the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Also hydrolyzes 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) in vivo. Also acts on 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and sphingosylphosphocholine. |
| Protein Name | Sphingomyelin Phosphodiesterase 2Lyso-Platelet-Activating Factor-Phospholipase CLyso-Paf-PlcNeutral SphingomyelinaseN-SmaseNsmaseNsmase1 |
| Database Links | Reactome: R-HSA-193681Reactome: R-HSA-5626978Reactome: R-HSA-9840310 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingomyelin Phosphodiesterase 2 antibodyAnti-Lyso-Platelet-Activating Factor-Phospholipase C antibodyAnti-Lyso-Paf-Plc antibodyAnti-Neutral Sphingomyelinase antibodyAnti-N-Smase antibodyAnti-Nsmase antibodyAnti-Nsmase1 antibodyAnti-SMPD2 antibody |
Information sourced from Uniprot.org