| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLK |
| Gene ID: | 9748 |
| Uniprot ID: | SLK_HUMAN |
| Immunogen Region: | 1-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human SLK (NP_055535.2). |
| Immunogen Sequence: | MSFFNFRKIFKLGSEKKKKQ YEHVKRDLNPEDFWEIIGEL GDGAFGKVYKAQNKETSVLA AAKVIDTKSEEELEDYMVEI DILASCDHPNIVKLLDAFYY ENNLWILIEFCAGGAVDAVM LELERPLTESQIQVVCKQTL DALNYLHDNKIIHRDLKAGN ILFTLDGDIKLADFGVSAKN TRTIQRRDSFIGTPYWMAPE VVMCETSKDRPYDYKADVWS LGITLIEMAE |
| Tissue Specificity | Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle. |
| Post Translational Modifications | Proteolytically cleaved by caspase-3. Autophosphorylated. |
| Function | Mediates apoptosis and actin stress fiber dissolution. |
| Protein Name | Ste20-Like Serine/Threonine-Protein Kinase Ste20-Like Kinase Hslk Ctcl Tumor Antigen Se20-9 Ste20-Related Serine/Threonine-Protein Kinase Ste20-Related Kinase Serine/Threonine-Protein Kinase 2 |
| Database Links | Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ste20-Like Serine/Threonine-Protein Kinase antibody Anti-Ste20-Like Kinase antibody Anti-Hslk antibody Anti-Ctcl Tumor Antigen Se20-9 antibody Anti-Ste20-Related Serine/Threonine-Protein Kinase antibody Anti-Ste20-Related Kinase antibody Anti-Serine/Threonine-Protein Kinase 2 antibody Anti-SLK antibody Anti-KIAA0204 antibody Anti-STK2 antibody |
Information sourced from Uniprot.org
