| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLITRK1 (410-460 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
SLITRK1 |
| Gene ID: |
114798 |
| Uniprot ID: |
SLIK1_HUMAN |
| Immunogen Region: |
410-460 aa |
| Specificity: |
Specific for SLITRK1. |
| Immunogen: |
A synthetic peptide from aa region 410-460 of human SLITRK1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Post Translational Modifications | Undergoes proteolytic cleavage that results in shedding of the ectodomain and cleavage of the C-terminal cytoplasmic tail. Glycosylated. Phosphorylation at Ser-695 is necessary for proper function in promoting neurite outgrowth. |
| Function | It is involved in synaptogenesis and promotes excitatory synapse differentiation. Enhances neuronal dendrite outgrowth. |
| Protein Name | Slit And Ntrk-Like Protein 1Leucine-Rich Repeat-Containing Protein 12 |
| Database Links | Reactome: R-HSA-388844 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedSynapse |
| Alternative Antibody Names | Anti-Slit And Ntrk-Like Protein 1 antibodyAnti-Leucine-Rich Repeat-Containing Protein 12 antibodyAnti-SLITRK1 antibodyAnti-KIAA1910 antibodyAnti-LRRC12 antibodyAnti-UNQ233 antibodyAnti-PRO266 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
