Western blot analysis of various lysates using SLC8A2 Rabbit polyclonal antibody (STJ118169) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-SLC8A2 antibody (360-450) (STJ118169)

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STJ118169
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC8A2
Gene ID: 6543
Uniprot ID: NAC2_HUMAN
Immunogen Region: 360-450
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1).
Immunogen Sequence: LMTGAGNVLRRHAADASRRA APAEGAGEDEDDGASRIFFE PSLYHCLENCGSVLLSVTCQ GGEGNSTFYVDYRTEDGSAK AGSDYEYSEGT
Function Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion.
Protein Name Sodium/Calcium Exchanger 2
Na(+/Ca(2+-Exchange Protein 2
Solute Carrier Family 8 Member 2
Database Links Reactome: R-HSA-418359
Reactome: R-HSA-425561
Reactome: R-HSA-5578775
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Perikaryon
Cell Projection
Dendrite
Dendritic Spine
Alternative Antibody Names Anti-Sodium/Calcium Exchanger 2 antibody
Anti-Na(+/Ca(2+-Exchange Protein 2 antibody
Anti-Solute Carrier Family 8 Member 2 antibody
Anti-SLC8A2 antibody
Anti-KIAA1087 antibody
Anti-NCX2 antibody

Information sourced from Uniprot.org

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