| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC8A2 |
| Gene ID: | 6543 |
| Uniprot ID: | NAC2_HUMAN |
| Immunogen Region: | 360-450 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1). |
| Immunogen Sequence: | LMTGAGNVLRRHAADASRRA APAEGAGEDEDDGASRIFFE PSLYHCLENCGSVLLSVTCQ GGEGNSTFYVDYRTEDGSAK AGSDYEYSEGT |
| Function | Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion. |
| Protein Name | Sodium/Calcium Exchanger 2 Na(+/Ca(2+-Exchange Protein 2 Solute Carrier Family 8 Member 2 |
| Database Links | Reactome: R-HSA-418359 Reactome: R-HSA-425561 Reactome: R-HSA-5578775 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane Perikaryon Cell Projection Dendrite Dendritic Spine |
| Alternative Antibody Names | Anti-Sodium/Calcium Exchanger 2 antibody Anti-Na(+/Ca(2+-Exchange Protein 2 antibody Anti-Solute Carrier Family 8 Member 2 antibody Anti-SLC8A2 antibody Anti-KIAA1087 antibody Anti-NCX2 antibody |
Information sourced from Uniprot.org