| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC8A2 (360-450) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC8A2 |
| Gene ID: |
6543 |
| Uniprot ID: |
NAC2_HUMAN |
| Immunogen Region: |
360-450 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1). |
| Immunogen Sequence: |
LMTGAGNVLRRHAADASRRA APAEGAGEDEDDGASRIFFE PSLYHCLENCGSVLLSVTCQ GGEGNSTFYVDYRTEDGSAK AGSDYEYSEGT |
| Function | Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion. |
| Protein Name | Sodium/Calcium Exchanger 2Na(+/Ca(2+-Exchange Protein 2Solute Carrier Family 8 Member 2 |
| Database Links | Reactome: R-HSA-418359Reactome: R-HSA-425561Reactome: R-HSA-5578775 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembranePerikaryonCell ProjectionDendriteDendritic Spine |
| Alternative Antibody Names | Anti-Sodium/Calcium Exchanger 2 antibodyAnti-Na(+/Ca(2+-Exchange Protein 2 antibodyAnti-Solute Carrier Family 8 Member 2 antibodyAnti-SLC8A2 antibodyAnti-KIAA1087 antibodyAnti-NCX2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
