| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC7A9 (1-100) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC7A9 |
| Gene ID: |
11136 |
| Uniprot ID: |
BAT1_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC7A9 (NP_055085.1). |
| Immunogen Sequence: |
MGDTGLRKRREDEKSIQSQE PKTTSLQKELGLISGISIIV GTIIGSGIFVSPKSVLSNTE AVGPCLIIWAACGVLATLGA LCFAELGTMITKSGGEYPYL |
| Tissue Specificity | Expressed in the brush border membrane in the kidney (at protein level). Kidney, small intestine, liver and placenta. |
| Function | Associates with SLC3A1 to form a functional transporter complex that mediates the electrogenic exchange between cationic amino acids and neutral amino acids, with a stoichiometry of 1:1. Has system b(0,+)-like activity with high affinity for extracellular cationic amino acids and L-cystine and lower affinity for intracellular neutral amino acids. Substrate exchange is driven by high concentration of intracellular neutral amino acids and the intracellular reduction of L-cystine to L-cysteine. Required for reabsorption of L-cystine and dibasic amino acids across the brush border membrane in renal proximal tubules. |
| Protein Name | B(0 -+-Type Amino Acid Transporter 1B(0 -+At1Glycoprotein-Associated Amino Acid Transporter B0 -+At1Solute Carrier Family 7 Member 9 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-352230Reactome: R-HSA-5619113Reactome: R-HSA-5660883 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-B(0 -+-Type Amino Acid Transporter 1 antibodyAnti-B(0 -+At1 antibodyAnti-Glycoprotein-Associated Amino Acid Transporter B0 -+At1 antibodyAnti-Solute Carrier Family 7 Member 9 antibodyAnti-SLC7A9 antibodyAnti-BAT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
