| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Sodium-and chloride-dependent taurine transporter (561-610 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC6A6 |
| Gene ID: | 6533 |
| Uniprot ID: | SC6A6_HUMAN |
| Immunogen Region: | 561-610 aa |
| Specificity: | TAUT Polyclonal Antibody detects endogenous levels of TAUT protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SLC6A6 at the amino acid range 561-610 |
| Post Translational Modifications | Taurine transport activity is down-regulated upon Ser-322 phosphorylation. |
| Function | Mediates sodium- and chloride-dependent transport of taurine. Mediates transport of beta-alanine. Can also mediate transport of hypotaurine and gamma-aminobutyric acid (GABA). Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. |
| Protein Name | Sodium- And Chloride-Dependent Taurine TransporterSolute Carrier Family 6 Member 6 |
| Database Links | Reactome: R-HSA-352230Reactome: R-HSA-442660 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Taurine Transporter antibodyAnti-Solute Carrier Family 6 Member 6 antibodyAnti-SLC6A6 antibody |
Information sourced from Uniprot.org