Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SLC5A5 |
Gene ID: | 6528 |
Uniprot ID: | SC5A5_HUMAN |
Immunogen Region: | 544-643 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 544-643 of human SLC5A5 (NP_000444.1). |
Immunogen Sequence: | ALISCLTGPTKRSTLAPGLL WWDLARQTASVAPKEEVAIL DDNLVKGPEELPTGNKKPPG FLPTNEDRLFFLGQKELEGA GSWTPCVGHDGGRDQQETNL |
Tissue Specificity | Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. |
Post Translational Modifications | Glycosylated. |
Function | Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland. Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate. |
Protein Name | Sodium/Iodide CotransporterNa(+/I(- CotransporterNatrium Iodide TransporterSodium-Iodide SymporterNa(+/I(- SymporterSolute Carrier Family 5 Member 5 |
Database Links | Reactome: R-HSA-209968Reactome: R-HSA-428643Reactome: R-HSA-5619096 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasm |
Alternative Antibody Names | Anti-Sodium/Iodide Cotransporter antibodyAnti-Na(+/I(- Cotransporter antibodyAnti-Natrium Iodide Transporter antibodyAnti-Sodium-Iodide Symporter antibodyAnti-Na(+/I(- Symporter antibodyAnti-Solute Carrier Family 5 Member 5 antibodyAnti-SLC5A5 antibodyAnti-NIS antibody |
Information sourced from Uniprot.org