Anti-SLC5A12 antibody (200-280) (STJ118617)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC5A12 (200-280) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC5A12 |
| Gene ID | 159963 |
| Uniprot ID | SC5AC_HUMAN |
| Immunogen Region | 200-280 |
| Immunogen Sequence | LIQGSTHAGGFHNVLEQSTN GSRLHIFDFDVDPLRRHTFW TITVGGTFTWLGIYGVNQST IQRCISCKTEKHAKLALYFN L |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 200-280 of human SLC5A12 (NP_848593.2). |
Additional Info
| Function | Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. |
| Protein Name | Sodium-Coupled Monocarboxylate Transporter 2Electroneutral Sodium Monocarboxylate CotransporterLow-Affinity Sodium-Lactate CotransporterSolute Carrier Family 5 Member 12 |
| Database Links | Reactome: R-HSA-427601 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinDetected At The Brush Border Membrane Of The KidneyColocalizes With Viementin In Mueller Cells |
| Alternative Antibody Names | Anti-Sodium-Coupled Monocarboxylate Transporter 2 antibodyAnti-Electroneutral Sodium Monocarboxylate Cotransporter antibodyAnti-Low-Affinity Sodium-Lactate Cotransporter antibodyAnti-Solute Carrier Family 5 Member 12 antibodyAnti-SLC5A12 antibodyAnti-SMCT2 antibody |
Information sourced from Uniprot.org