• Western blot analysis of lysates from COLO cells, using SLC4A8/10 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HUVECcells using SLC4A8/10 antibody.
  • Western blot analysis of COLO cells using SLC4A8/10 Polyclonal Antibody diluted at 1：500

Anti-SLC4A8/10 antibody (411-460 aa) (STJ95681)

SKU:
STJ95681

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Electroneutral sodium bicarbonate exchanger 1 and Sodium-driven chloride bicarbonate exchanger (411-460 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC4A8
SLC4A10
Gene ID: 9498
57282
Uniprot ID: S4A8_HUMAN
S4A10_HUMAN
Immunogen Region: 411-460 aa
Specificity: SLC4A8/10 Polyclonal Antibody detects endogenous levels of SLC4A8/10 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SLC4A8/10 at the amino acid range 411-460
Function Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
Protein Name Electroneutral Sodium Bicarbonate Exchanger 1
Electroneutral Na(+-Driven Cl-Hco3 Exchanger
Solute Carrier Family 4 Member 8
K-Nbc3
Database Links Reactome: R-HSA-425381
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Electroneutral Sodium Bicarbonate Exchanger 1 antibody
Anti-Electroneutral Na(+-Driven Cl-Hco3 Exchanger antibody
Anti-Solute Carrier Family 4 Member 8 antibody
Anti-K-Nbc3 antibody
Anti-SLC4A8 antibody
Anti-KIAA0739 antibody
Anti-NBC antibody
Anti-NBC3 antibody
Anti-NDCBE1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance