| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC4A1 is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1: 3000 is recommended for WB and 1:1000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
Slc4a1 |
| Gene ID: |
20533 |
| Uniprot ID: |
B3AT_MOUSE |
| Specificity: |
Specific for SLC4A1. |
| Immunogen: |
A synthetic peptide from mouse Band 3 anion transport protein (SLC4A1, CD233) conjugated to blue carrier protein was used as the antigen. |
| Function | Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Component of the ankyrin-1 complex of the erythrocyte membrane.required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. |
| Protein Name | Band 3 Anion Transport ProteinAnion Exchange Protein 1Ae 1Anion Exchanger 1Meb3Solute Carrier Family 4 Member 1Cd Antigen Cd233 |
| Database Links | Reactome: R-MMU-1237044Reactome: -MMU-1247673Reactome: -MMU-425381 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneDetected In The Erythrocyte Cell Membrane And On The Basolateral Membrane Of Alpha-Intercalated Cells In The Collecting Duct In The Kidney |
| Alternative Antibody Names | Anti-Band 3 Anion Transport Protein antibodyAnti-Anion Exchange Protein 1 antibodyAnti-Ae 1 antibodyAnti-Anion Exchanger 1 antibodyAnti-Meb3 antibodyAnti-Solute Carrier Family 4 Member 1 antibodyAnti-Cd Antigen Cd233 antibodyAnti-Slc4a1 antibodyAnti-Ae1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
