• STJ72481 (0. 1µg/ml) staining of Human Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SLC47A2 antibody (Internal) (STJ72481)

SKU:
STJ72481-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-SLC47A2 (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.1-0.3µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SLC47A2
Gene ID: 146802
Uniprot ID: S47A2_HUMAN
Immunogen Region: Internal
Accession Number: NP_690872.2; NP_001093116.1
Specificity: This antibody is expected to recognize both reported isoforms (NP_690872.2; NP_001093116.1).
Immunogen Sequence: QRAESTATRPGPEK
Function Multidrug efflux pump that functions as a H(+)/organic cation antiporter. Mediates the efflux of cationic compounds, such as the model cations, tetraethylammonium (TEA) and 1-methyl-4-phenylpyridinium (MPP+), the platinum-based drug oxaliplatin or weak bases that are positively charged at physiological pH, cimetidine, the platinum-based drugs cisplatin and oxaliplatin or the antidiabetic drug metformin. Mediates the efflux of endogenous compounds such as, creatinine, thiamine and estrone-3-sulfate. Plays a physiological role in the excretion of drugs, toxins and endogenous metabolites through the kidney. Isoform 6: Non-functional protein.
Protein Name Multidrug And Toxin Extrusion Protein 2
Mate-2
Hmate-2
Kidney-Specific H(+/Organic Cation Antiporter
Solute Carrier Family 47 Member 2
Database Links Reactome: R-HSA-425366
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Detected In The Renal Urinary Tubules
Isoform 6: Apical Cell Membrane
Localized At The Brush Border Membranes Of The Proximal Tubules
Alternative Antibody Names Anti-Multidrug And Toxin Extrusion Protein 2 antibody
Anti-Mate-2 antibody
Anti-Hmate-2 antibody
Anti-Kidney-Specific H(+/Organic Cation Antiporter antibody
Anti-Solute Carrier Family 47 Member 2 antibody
Anti-SLC47A2 antibody
Anti-MATE2 antibody

Information sourced from Uniprot.org

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