Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Sodium-coupled neutral amino acid symporter 1 is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC38A1 |
Gene ID: |
81539 |
Uniprot ID: |
S38A1_HUMAN |
Specificity: |
This antibody detects endogenous levels of SLC38A1 at Human, Mouse, Rat |
Immunogen: |
Synthesized peptide derived from human SLC38A1 |
Post Translational Modifications | N-glycosylation plays an important role in the L-glutamine transport. |
Function | Symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane. The transport is elctrogenic, pH dependent and driven by the Na(+) electrochemical gradient. Participates in the astroglia-derived glutamine transport into GABAergic interneurons for neurotransmitter GABA de novo synthesis. May also contributes to amino acid transport in placental trophoblasts. Also regulates synaptic plasticity. |
Protein Name | Sodium-Coupled Neutral Amino Acid Symporter 1Amino Acid Transporter A1N-System Amino Acid Transporter 2Solute Carrier Family 38 Member 1System A Amino Acid Transporter 1System N Amino Acid Transporter 1 |
Database Links | Reactome: R-HSA-210455Reactome: R-HSA-352230 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinRestricted To The Somatodendritic Compartment Of NeuronsFound In The Cellular Processes Of Neurons In The Developing Brain |
Alternative Antibody Names | Anti-Sodium-Coupled Neutral Amino Acid Symporter 1 antibodyAnti-Amino Acid Transporter A1 antibodyAnti-N-System Amino Acid Transporter 2 antibodyAnti-Solute Carrier Family 38 Member 1 antibodyAnti-System A Amino Acid Transporter 1 antibodyAnti-System N Amino Acid Transporter 1 antibodyAnti-SLC38A1 antibodyAnti-ATA1 antibodyAnti-NAT2 antibodyAnti-SAT1 antibodyAnti-SNAT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance