| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-UDP-N-acetylglucosamine transporter (263-313 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC35A3 |
| Gene ID: | 23443 |
| Uniprot ID: | S35A3_HUMAN |
| Immunogen Region: | 263-313 aa |
| Specificity: | This antibody detects endogenous levels of S35A3 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human S35A3 at the amino acid range 263-313 |
| Function | Transports diphosphate-N-acetylglucosamine (UDP-GlcNAc) from the cytosol into the lumen of the Golgi apparatus, functioning as an antiporter that exchanges UDP-N-acetyl-alpha-D-glucosamine for UMP. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate highly branched, multiantennary complex N-glycans and keratan sulfate. However, the exact role of SLC35A3 still needs to be elucidated, it could be a member of a catalytically more efficient multiprotein complex rather than function independently as a single transporter. |
| Protein Name | Udp-N-Acetylglucosamine TransporterGolgi Udp-Glcnac TransporterSolute Carrier Family 35 Member A3 |
| Database Links | Reactome: R-HSA-5619083Reactome: R-HSA-727802 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Udp-N-Acetylglucosamine Transporter antibodyAnti-Golgi Udp-Glcnac Transporter antibodyAnti-Solute Carrier Family 35 Member A3 antibodyAnti-SLC35A3 antibody |
Information sourced from Uniprot.org