| Short Description : | Rabbit polyclonal SLC30A6 (252-461) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC30A6 |
| Gene ID: | 55676 |
| Uniprot ID: | ZNT6_HUMAN |
| Immunogen Region: | 252-461 |
| Immunogen Sequence: | KVLLQTTPPHVIGQLDKLIR EVSTLDGVLEVRNEHFWTLG FGSLAGSVHVRIRRDANEQM VLAHVTNRLYTLVSTLTVQI FKDDWIRPALLSGPVAANVL NFSDHHVIPMPLLKGTDDLN PVTSTPAKPSSPPPEFSFNT PGKNVNPVILLNTQTRPYGF GLNHGHTPYSSMLNQGLGVP GIGATQGLRTGFTNIPSRYG TNNRIGQPRP |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 252-461 of human SLC30A6 (NP_060434.2). |
| Tissue Specificity | Expressed in brain.especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B-cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis. |
| Function | Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis. |
| Protein Name | Zinc Transporter 6Znt-6Solute Carrier Family 30 Member 6 |
| Database Links | |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Zinc Transporter 6 antibodyAnti-Znt-6 antibodyAnti-Solute Carrier Family 30 Member 6 antibodyAnti-SLC30A6 antibodyAnti-ZNT6 antibody |
Information sourced from Uniprot.org
