| Host: | Rabbit |
| Applications: | WB/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S2MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:4000IP:0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC2A3 |
| Gene ID: | 6515 |
| Uniprot ID: | GTR3_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLUT3/SLC2A3 (P11169). |
| Immunogen Sequence: | MGTQKVTPALIFAITVATIG SFQFGYNTGVINAPEKIIKE FINKTLTDKGNAPPSEVLLT SLWSLSVAIFSVGGMIGSFS VGLFVNRFGRRNSMLIVNLL |
| Tissue Specificity | Highly expressed in brain. Expressed in many tissues. |
| Function | Facilitative glucose transporter. Can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. Required for mesendoderm differentiation. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 3Glucose Transporter Type 3 - BrainGlut-3 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-196836Reactome: R-HSA-6798695Reactome: R-HSA-9022699 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPerikaryonCell ProjectionLocalized To Densely Spaced Patches Along Neuronal Processes |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 3 antibodyAnti-Glucose Transporter Type 3 - Brain antibodyAnti-Glut-3 antibodyAnti-SLC2A3 antibodyAnti-GLUT3 antibody |
Information sourced from Uniprot.org
