• mouse kidney tissue was stained with Anti-GLUT-1 (ABT-GLUT1) Antibody
  • mouse kidney tissue was stained with Anti-GLUT-1 (ABT-GLUT1) Antibody
  • Human colon carcinoma tissue was stained with Anti-GLUT-1 (ABT-GLUT1) Antibody

Anti-SLC2A1 antibody (400-492 aa) [ABT-GLUT1] (STJ196925)

SKU:
STJ196925

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Solute carrier family 2, facilitated glucose transporter member 1 (400-492 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: ABT-GLUT1
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:100-500
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC2A1
Gene ID: 6513
Uniprot ID: GTR1_HUMAN
Immunogen Region: 400-492 aa
Specificity: This antibody detects endogenous levels of human GLUT-1. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section. The antibody was
Immunogen: Synthesized peptide derived from the human GLUT-1 at the amino acid range 400-492
Post Translational Modifications Phosphorylation at Ser-226 by PKC promotes glucose uptake by increasing cell membrane localization.
Function Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity.can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation.
Protein Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1
Glucose Transporter Type 1 - Erythrocyte/Brain
Glut-1
Hepg2 Glucose Transporter
Database Links Reactome: R-HSA-189200
Reactome: R-HSA-196836
Reactome: R-HSA-422356
Reactome: R-HSA-5619043
Reactome: R-HSA-5653890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Melanosome
Photoreceptor Inner Segment
Localizes Primarily At The Cell Surface
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1 antibody
Anti-Glucose Transporter Type 1 - Erythrocyte/Brain antibody
Anti-Glut-1 antibody
Anti-Hepg2 Glucose Transporter antibody
Anti-SLC2A1 antibody
Anti-GLUT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance