| Short Description : | Rabbit polyclonal SLC28A3 (612-691) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC28A3 |
| Gene ID: | 64078 |
| Uniprot ID: | S28A3_HUMAN |
| Immunogen Region: | 612-691 |
| Immunogen Sequence: | LSSTPVDINCHHVLENAFNS TFPGNTTKVIACCQSLLSST VAKGPGEVIPGGNHSLYSLK GCCTLLNPSTFNCNGISNTF |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 612-691 of human SLC28A3 (NP_071410.1). |
| Tissue Specificity | Expressed in pancreas, bone marrow, trachea, mammary gland, liver, prostate, and regions of intestine, brain, lung, placenta, testis, kidney, and heart. |
| Function | Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Transports uridine. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine. |
| Protein Name | Solute Carrier Family 28 Member 3Concentrative Na(+-Nucleoside Cotransporter 3Cnt 3Hcnt3 |
| Database Links | Reactome: R-HSA-83936Reactome: R-HSA-9748787Reactome: R-HSA-9755088 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 2: Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Solute Carrier Family 28 Member 3 antibodyAnti-Concentrative Na(+-Nucleoside Cotransporter 3 antibodyAnti-Cnt 3 antibodyAnti-Hcnt3 antibodyAnti-SLC28A3 antibodyAnti-CNT3 antibody |
Information sourced from Uniprot.org
