Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SLC28A3 (612-691) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC28A3 |
Gene ID: |
64078 |
Uniprot ID: |
S28A3_HUMAN |
Immunogen Region: |
612-691 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 612-691 of human SLC28A3 (NP_071410.1). |
Immunogen Sequence: |
LSSTPVDINCHHVLENAFNS TFPGNTTKVIACCQSLLSST VAKGPGEVIPGGNHSLYSLK GCCTLLNPSTFNCNGISNTF |
Tissue Specificity | Expressed in pancreas, bone marrow, trachea, mammary gland, liver, prostate, and regions of intestine, brain, lung, placenta, testis, kidney, and heart. |
Function | Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Transports uridine. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine. |
Protein Name | Solute Carrier Family 28 Member 3Concentrative Na(+-Nucleoside Cotransporter 3Cnt 3Hcnt3 |
Database Links | Reactome: R-HSA-83936Reactome: R-HSA-9748787Reactome: R-HSA-9755088 |
Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 2: Endoplasmic Reticulum Membrane |
Alternative Antibody Names | Anti-Solute Carrier Family 28 Member 3 antibodyAnti-Concentrative Na(+-Nucleoside Cotransporter 3 antibodyAnti-Cnt 3 antibodyAnti-Hcnt3 antibodyAnti-SLC28A3 antibodyAnti-CNT3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance