| Short Description : | Rabbit polyclonal SLC26A9 (500-660) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC26A9 |
| Gene ID: | 115019 |
| Uniprot ID: | S26A9_HUMAN |
| Immunogen Region: | 500-660 |
| Immunogen Sequence: | RNGYALAQVMDTDIYVNPKT YNRAQDIQGIKIITYCSPLY FANSEIFRQKVIAKTGMDPQ KVLLAKQKYLKKQEKRRMRP TQQRRSLFMKTKTVSLQELQ QDFENAPPTDPNNNQTPANG TSVSYITFSPDSSSPAQSEP PASAEAPGEPSDMLASVPPF V |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-660 of human SLC26A9 (NP_443166.1). |
| Tissue Specificity | Predominantly expressed in lung at the luminal side of the bronchiolar and alveolar epithelium of lung. To a lower extent, also expressed in pancreas and prostate. |
| Function | Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane. |
| Protein Name | Solute Carrier Family 26 Member 9Anion Transporter/Exchanger Protein 9 |
| Database Links | Reactome: R-HSA-427601 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndomembrane SystemLocalization To The Cell Membrane Is Inhibited By Wnk Kinases (Wnk1Wnk2Wnk3 Or Wnk4) In A Kinase-Independent Mechanism |
| Alternative Antibody Names | Anti-Solute Carrier Family 26 Member 9 antibodyAnti-Anion Transporter/Exchanger Protein 9 antibodyAnti-SLC26A9 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and ANKRD52 knockout (KO) 293T cells, using [KO Validated] ANKRD52 Rabbit polyclonal antibody (STJ11100834) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89769/358241/STJ11100834_1__55275.1713122574.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ANKRD52 knockout (KO) 293T cells, using [KO Validated] ANKRD52 Rabbit polyclonal antibody (STJ11100834) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
