Western blot analysis of various lysates using SLC25A12 Rabbit polyclonal antibody (STJ113288) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-SLC25A12 antibody (1-180) (STJ113288)

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STJ113288
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC25A12
Gene ID: 8604
Uniprot ID: S2512_HUMAN
Immunogen Region: 1-180
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SLC25A12 (NP_003696.2).
Immunogen Sequence: MAVKVQTTKRGDPHELRNIF LQYASTEVDGERYMTPEDFV QRYLGLYNDPNSNPKIVQLL AGVADQTKDGLISYQEFLAF ESVLCAPDSMFIVAFQLFDK SGNGEVTFENVKEIFGQTII HHHIPFNWDCEFIRLHFGHN RKKHLNYTEFTQFLQELQLE HARQAFALKDKSKSGMISGL
Tissue Specificity Expressed predominantly in the heart and skeletal muscle, weakly in brain and kidney.
Function Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation.
Protein Name Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial
Araceli Hiperlarga
Aralar
Aralar1
Mitochondrial Aspartate Glutamate Carrier 1
Solute Carrier Family 25 Member 12
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-8963693
Reactome: R-HSA-9856872
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial antibody
Anti-Araceli Hiperlarga antibody
Anti-Aralar antibody
Anti-Aralar1 antibody
Anti-Mitochondrial Aspartate Glutamate Carrier 1 antibody
Anti-Solute Carrier Family 25 Member 12 antibody
Anti-SLC25A12 antibody
Anti-AGC1 antibody
Anti-ARALAR1 antibody

Information sourced from Uniprot.org

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