| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC25A12 (1-180) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC25A12 |
| Gene ID: |
8604 |
| Uniprot ID: |
S2512_HUMAN |
| Immunogen Region: |
1-180 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SLC25A12 (NP_003696.2). |
| Immunogen Sequence: |
MAVKVQTTKRGDPHELRNIF LQYASTEVDGERYMTPEDFV QRYLGLYNDPNSNPKIVQLL AGVADQTKDGLISYQEFLAF ESVLCAPDSMFIVAFQLFDK SGNGEVTFENVKEIFGQTII HHHIPFNWDCEFIRLHFGHN RKKHLNYTEFTQFLQELQLE HARQAFALKDKSKSGMISGL |
| Tissue Specificity | Expressed predominantly in the heart and skeletal muscle, weakly in brain and kidney. |
| Function | Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. |
| Protein Name | Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - MitochondrialAraceli HiperlargaAralarAralar1Mitochondrial Aspartate Glutamate Carrier 1Solute Carrier Family 25 Member 12 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-70263Reactome: R-HSA-8963693 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial antibodyAnti-Araceli Hiperlarga antibodyAnti-Aralar antibodyAnti-Aralar1 antibodyAnti-Mitochondrial Aspartate Glutamate Carrier 1 antibodyAnti-Solute Carrier Family 25 Member 12 antibodyAnti-SLC25A12 antibodyAnti-AGC1 antibodyAnti-ARALAR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
