Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SLC24A4 |
Gene ID: | 123041 |
Uniprot ID: | NCKX4_HUMAN |
Immunogen Region: | 200-300 |
Specificity: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC24A4 (NP_705932.2). |
Immunogen Sequence: | WWAVCRDSVYYTISVIVLIV FIYDEQIVWWEGLVLIILYV FYILIMKYNVKMQAFFTVKQ KSIANGNPVNSELEAGNDFY DGSYDDPSVPLLGQVKEKPQ Y |
Tissue Specificity | Expressed abundantly in all regions of the brain, aorta, lung and thymus. Expressed at lower levels in the stomach and intestine. |
Function | Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis. |
Protein Name | Sodium/Potassium/Calcium Exchanger 4Na(+/K(+/Ca(2+-Exchange Protein 4Solute Carrier Family 24 Member 4 |
Database Links | Reactome: R-HSA-425561Reactome: R-HSA-5619055 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasm |
Alternative Antibody Names | Anti-Sodium/Potassium/Calcium Exchanger 4 antibodyAnti-Na(+/K(+/Ca(2+-Exchange Protein 4 antibodyAnti-Solute Carrier Family 24 Member 4 antibodyAnti-SLC24A4 antibodyAnti-NCKX4 antibody |
Information sourced from Uniprot.org