Anti-SLC22A9 antibody (STJA0008391)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SLC22A9
General Information
| Short Description | Rabbit polyclonal anti-Organic anion transporter 7 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC22A9 |
| Gene ID | 114571 |
| Uniprot ID | S22A9_HUMAN |
| Immunogen | Synthesized peptide derived from human SLC22A9 |
| Specificity | This antibody detects endogenous levels of SLC22A9 at Human |
Additional Info
| Function | Sodium-independent organic anion transporter, exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones such as estrone 3-sulfate (E1S) and dehydroepiandrosterone sulfate (DHEAS). Can transport the statin pravastatin and may contribute to its disposition into the hepatocytes when the function of OATPs is compromised. It is specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate (propanoate), butyrate (butanoate) and valerate (pentanoate). May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs, in particular butanoate, at the sinusoidal membrane of hepatocytes. |
| Protein Name | Organic Anion Transporter 7Oat7Organic Anion/Short-Chain Fatty Acid ExchangerSolute Carrier Family 22 Member 9 |
| Database Links | |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinEnriched At The Sinusoidal Part Of The Plasma Membrane |
| Alternative Antibody Names | Anti-Organic Anion Transporter 7 antibodyAnti-Oat7 antibodyAnti-Organic Anion/Short-Chain Fatty Acid Exchanger antibodyAnti-Solute Carrier Family 22 Member 9 antibodyAnti-SLC22A9 antibodyAnti-hOAT4 antibodyAnti-OAT7 antibodyAnti-UST3 antibody |
Information sourced from Uniprot.org