Anti-SLC1A7 antibody (Internal) (STJ72720)

SKU:
STJ72720-100

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Host: Goat
Applications: Pep-ELISA
Reactivity: Human/Mouse/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-SLC1A7 (Internal) is suitable for use in ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SLC1A7
Gene ID: 6512
Uniprot ID: EAA5_HUMAN
Immunogen Region: Internal
Accession Number: NP_006662.3
Immunogen Sequence: RTRRLSPQEISYFQ
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Acts primarily as an inhibitory glutamate-gated chloride channel being a major inhibitory presynaptic receptor at mammalian rod bipolar cell axon terminals. Glutamate binding gates a large Cl(-) conductance that mediates inhibition, affecting visual processing in the retina.
Protein Name Excitatory Amino Acid Transporter 5
Retinal Glutamate Transporter
Solute Carrier Family 1 Member 7
Database Links Reactome: R-HSA-210500
Reactome: R-HSA-425393
Cellular Localisation Photoreceptor Inner Segment Membrane
Multi-Pass Membrane Protein
Synaptic Cell Membrane
Located In Both Cone And Rod Photoreceptor Terminals And In Axon Terminals Of Rod Bipolar Cells
Alternative Antibody Names Anti-Excitatory Amino Acid Transporter 5 antibody
Anti-Retinal Glutamate Transporter antibody
Anti-Solute Carrier Family 1 Member 7 antibody
Anti-SLC1A7 antibody
Anti-EAAT5 antibody

Information sourced from Uniprot.org

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